Pandora: Probing safety of nano-objects by defining immune responses of environmental organisms

A Marie Skłodowska-Curie Actions Innovative Training Network funded by the EU Horizon 2020 Framework Programme

The Pandora Researchers at their kick-off meeting in Barcelona, 2017

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Project Overview

Nanoparticles are sub-microscopic particles, ranging in size from 1 to 100 nm, which are currently used in numerous applications including medicine, cosmetics and textiles. Common nanoparticles used in these industries include zinc, copper, silver and magnesium. Until now, the lasting effects of nanoparticles has remained unclear and their ability to pass into the cytoplasm of cells has triggered the need to investigate their use, and how they may affect living organisms.

The Pandora network aims to investigate the effect of these nanoparticles on the immune and defensive responses of earth and marine organisms in parallel to humans. The aim is to identify common reactivity across immune defence evolution.

This includes collaboration between the academic and industrial sectors, involving research centres, academic institutions and SMEs with experience in further education and training and expertise in the scientific field. This is a multidisciplinary project which will provide training of 11 early-stage researchers into the issue of immuno-nanosafety which will pave the way for an integrated approach to environmental nanosafety.

Beneficiaries involved have expertise in the following fields: immunology, biochemistry, immunochemistry, cell biology, developmental biology, marine biology, microbiology, molecular biology, pharmacology, toxicology and ecotoxicology, biotechnology, chemistry and nanotechnology together with experience in project management which will allow the trainee researchers to identify common mechanisms/markers across species that could be used for novel assays for assessing immune-nanosafety. They will also acquire key transferrable skills which will lead them to become leaders in this emerging field of academic and industrial research.

To read more about the Pandora Project, click the logo below.