AvantiCell provides an 'off-the-shelf' cell-based screening service offering a range of cell types and assay readouts. The service is available for all level of sample throughput and sample composition.

Cell Types

• For breast cancer applications, choose from:

Human breast cancer cell line HMT3909S8

Human luminal epithelial cell line 3.006

Human primary luminal epithelial cell line LEP-1

Human primary myoepithelial cell line MEP-1

• For liver cancer applications, choose from:

Liver Hepatocarcinoma cell line HepG2

Liver primary hepatocyte (launch autumn 2009 - please enquire)

• For neurodegeneration applications, choose:

UPS1 cell line (launch autumn 2009 - please enquire)

Assay Readouts

• Readouts measuring generic parameters of cell health
• (cell number, proliferation, apoptosis, cytotoxicity)
• Readouts measuring neurodegeneration - choose
• from screening options for preventive or remedial
• therapeutics

Sample Throughput

• 96-multiwell plate format - analysis scalable from
• single samples to multi-plate medium-throughput
• screening

• 384-well plate format for high throughput - due for
• launch winter 2009

Assay Performance

• Sensitive, fluorescence intensity readout
• Robust performance and reproducibility between
• assays and projects

Service Delivery

• Sample analysis and service delivery to tight
• deadlines

• Full data analysis and quality control using
• appropriate assay controls
• Report delivery in hard copy and electronic formats,
• with optional oral presentation

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